[3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester → 4-Isopropyl-6-[5-(4-morpholin-4-yl-phenylamino)-[1,2,3]triazol-1-yl]-benzene-1,3-diol

Participants

Reaction Steps

A solution of the intermediate from Step E in DCM/TFA (1/1 5 ml) was stirred for 12 hours at RT. The reaction mixture was concentrated under reduced pressure and the crude reaction mixture was purified by column chromatography (DCM/MeOH: 95/5). The title compound was obtained as slightly brown solid.

Provenance & Evidence