HCID 21221808, compound → Suberic acid

HRID 623719Notes

Reaction equation

HRID 623719 reaction equation
[C:1]([OH:12])(=[O:11])[CH2:2][CH2:3][C:4]#[C:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9]>[Pd].C(O)C>[C:1]([OH:12])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9]

Participants

4

Reactant 1

HCID 21221808HCID 21221808, compound

Product 1

HCID 10457Suberic acidYield 68%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

10% Palladium on carbon (10% wt) was added to a solution of oct-4-ynedioic acid I-56 in ethanol. The mixture was degassed with argon and then stirred under an atmosphere of H2 for 14 h. The mixture was filtered through celite and concentrated to afford octanedioic acid in 68% yield.

Workup

  1. customThe mixture was degassed with argon
  2. filtrationThe mixture was filtered through celite
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-2567ce8e7c0144cd8e898e9d17b43938
Source dataset
uspto-grants-2016_04
Patent number
US09303002B2

Reaction notes

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