HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium ethoxide → 6-Bromo-3-(4-chlorophenoxy)-2-ethoxy-4-(trifluoromethyl)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | 6-bromo-3-(4-chlorophenoxy)-4-(trifluoromethyl)quinolin-2(1H)-one | HCID 86715448 | — |
| Product | 6-Bromo-3-(4-chlorophenoxy)-2-ethoxy-4-(trifluoromethyl)quinoline | HCID 86715450 | — |
Reaction Steps
The title compound was prepared using 6-bromo-2-chloro-3-(4-chlorophenoxy)-4-(trifluoromethyl)quinoline (Intermediate 7, step d) in place of (4-chlorophenyl)(2,4-dichloro-3-phenoxyquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)methanol (Example 1) according to the procedure of Example 2 except only one equivalent of sodium ethoxide was used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09303015B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-09c16e024121407f9657f63f6939b2e9 |
| Source note | uspto-grants-2016_04 |