HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-bromo-2-(2-(4-cyanophenoxy)acetamido)benzoate → 4-((6-Bromo-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)oxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-bromo-2-(2-(4-cyanophenoxy)acetamido)benzoate | HCID 8112554 | — |
| Reactant | 6-Bromo-4-hydroxy-3-phenoxyquinolin-2(1H)-one | HCID 86715444 | — |
| Product | 4-((6-Bromo-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)oxy)benzonitrile | HCID 86715455 | — |
Reaction Steps
The title compound was prepared using methyl 5-bromo-2-(2-(4-cyanophenoxy)acetamido)benzoate (Intermediate 10, step b) in place of methyl 5-bromo-2-(2-phenoxyacetamido)benzoate (Intermediate 5, step a) according to the procedure described in Intermediate 5, step b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09303015B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-023213d9474b410fa49c7f27a6d78ec7 |
| Source note | uspto-grants-2016_04 |