Hydrochloric Acid → HCID 68283373, compound

Participants

Reaction Steps

To a stirred solution of 5-(3-morpholinophenyl)oxazole-4-carboxylate (900 mg, 2.98 mmol) in THF (29 mL) was added 1N aq. NaOH-solution (14 mL) and the resulting mixture was stirred at rt overnight. The reaction mixture was poured into 1N aq. HCl-solution and extracted with EtOAc (85 mL). The org. layer was dried (MgSO4), filtered and concentrated to dryness to afford the title compound as a yellow solid which was used without further purification. LC-MS conditions A: tR=0.70 min, [M+H]+=274.99.

Provenance & Evidence