Cesium carbonate → HCID 50999752, compound

Participants

Reaction Conditions

Reaction Steps

To 4-nitro-1H-pyrazole (220 mg, 1.95 mmol) in acetonitrile (10 mL), Cs2CO3 (697 mg, 2.14 mmol) and (2-bromoethoxy)benzene (439 mg, 2.14 mmol) was added. The resulting mixture was refluxed (80° C.) for 40 min and then let stir at rt overnight. The reaction mixture was filtered, the filter cake washed with DCM and the filtrate concentrated in vacuo to obtain 4-nitro-1-(2-phenoxyethyl)-1H-pyrazole as a crude solid which was used without further purification. LC-MS conditions A: tR=0.85 min, [M+H]+=no ionization.

Provenance & Evidence