HCID 86704210, compound → HCID 68283106, compound

Participants

Reaction Steps

To 4,6-dimethoxy-N-(2-(4-nitro-1H-pyrazol-1-yl)ethyl)pyrimidin-2-amine (3.39 g, 11.54 mmol) in EtOAc (8.0 mL, degassed) and EtOH (32 mL, degassed), PtO2 (1.23 g, 1.15 mmol) was added and the reaction mixture was stirred at rt under a H2-atmosphere for 3 h. The mixture was diluted with EtOH, filtered over celite and the filter cake was rinsed with EtOH. The filtrate was concentrated to obtain the title compound of a pale pink solid. LC-MS conditions A: tR=0.42 min, [M+H]+=265.13.

Provenance & Evidence