N-(1-(2-Aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide → N-(1-(2-Aminoethyl)-1H-imidazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide

HRID 624075Notes

Reaction equation

HRID 624075 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH:8]=[C:7]([NH:9][C:10]([C:12]2[N:13]=[CH:14][O:15][C:16]=2[C:17]2[CH:18]=[C:19]([CH3:23])[CH:20]=[CH:21][CH:22]=2)=[O:11])C=N1.[NH:24]1C=C(N)N=[CH:25]1>>[NH2:1][CH2:2][CH2:3][N:4]1[CH:8]=[C:7]([NH:9][C:10]([C:12]2[N:13]=[CH:14][O:15][C:16]=2[C:17]2[CH:18]=[C:19]([CH3:23])[CH:20]=[CH:21][CH:22]=2)=[O:11])[N:24]=[CH:25]1

Participants

3

Reactant 2

HCID 86704224N-(1-(2-Aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamideHCID 178508046HCID 178508046, compound

Product 1

HCID 86704226N-(1-(2-Aminoethyl)-1H-imidazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide

Procedure

The title compound was synthesized according to above mentioned procedure for N-(1-(2-aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide, starting from 1H-imidazol-4-amine. LC-MS conditions B: tR=0.47 min, [M+H]+=312.29.

Sources & evidence

ORD record
ord-e8879e42bc2a4430b51a5ebce7aef053
Source dataset
uspto-grants-2016_04
Patent number
US09303023B2

Reaction notes

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