HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21918751, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Reactant | tert-butyl N-(pyrrolidin-3-yl)carbamate | HCID 2757234 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21918751 | HCID 21918751 | — |
Reaction Steps
A solution of 1-fluoro-4-nitrobenzene (508 mg, 3.6 mmol) and tert-butyl pyrrolidin-3-ylcarbamate (671 mg, 3.6 mmol) in N,N-dimethylformamide (7 mL) was heated at 55° C. for 1.5 hours and then stirred overnight at room temperature. The reaction mixture was poured into water and the suspension was filtered with water washes to provide the title compound after drying.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302989B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-dd24d966492848a5b6bae6f283608a51 |
| Source note | uspto-grants-2016_04 |