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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624142Generated: October 30, 2026

Acetyl chloride → HCID 57509968, compound

https://huagongshe.com/reaction/624142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantHCID 57509898HCID 57509898—
ReactantHCID 68754543HCID 68754543—
ProductHCID 57509968HCID 57509968—

Reaction Steps

The title compound was prepared as described in Example 278, substituting benzoyl chloride for acetyl chloride and N-(isoindolin-5-yl)isoindoline-2-carboxamide for 5-amino-N-(4-(propylcarbamoyl)phenyl)isoindoline-2-carboxamide. 1H NMR (400 MHz, DMSO-d6) δ ppm 8.40 (d, J=8.8 Hz, 1H), 7.59-7.67 (m, 3H), 7.11-7.52 (m, 9H), 4.68-4.84 (m, 8H); MS (ESI(+)) m/e 384 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09302989B2
Source datasetuspto-grants-2016_04
ORD IDord-3762b0cfd8fd4db282c91e45ddf546a5
Source noteuspto-grants-2016_04