HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-isocyanatobenzoate → HCID 57510219, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-isocyanatobenzoate | HCID 280454 | — |
| Reactant | Isoindoline | HCID 422478 | — |
| Reactant | (2,3-dihydro-1H-isoindol-5-yl)methanol hydrochloride | HCID 68754933 | — |
| Product | HCID 57510219 | HCID 57510219 | — |
Reaction Steps
The title compound was prepared as described in Example 1A, substituting (4-isocyanatobutyl)benzene for methyl 4-isocyanatobenzoate and isoindolin-5-ylmethanol hydrochloride for isoindoline. 1H NMR (300 MHz, DMSO-d6) δ ppm 7.32-7.12 (m, 8H), 6.32-6.24 (m, 1H), 5.16 (t, J=5.6 Hz, 1H), 4.54 (bs, 4H), 4.49 (d, J=5.7 Hz, 2H), 3.14-3.05 (m, 2H), 2.64-2.54 (m, 2H), 1.63-1.39 (m, 4H); MS (ESI(+)) m/e 325 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302989B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-6af9f35b8c6344bba2f922388553ded6 |
| Source note | uspto-grants-2016_04 |