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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624245Generated: November 1, 2026

3-Phenylpropylamine → HCID 57510563, compound

https://huagongshe.com/reaction/624245

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PhenylpropylamineHCID 16259—
Reactant(R)-Tetrahydro-3-furoic acidHCID 4661317—
ReactantHCID 62230337HCID 62230337—
ProductHCID 57510563HCID 57510563—

Reaction Steps

The title compound was prepared as described in Example 1C, substituting N-(4-(piperidin-4-yl)phenyl)isoindoline-2-carboxamide for 3-phenylpropan-1-amine and tetrahydrofuran-3-carboxylic acid for 4-(isoindoline-2-carboxamido)benzoic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 8.26 (s, 1H), 7.46 (m, 2H), 7.31 (m, 4H), 7.12 (m, 2H), 4.74 (bs, 4H), 4.53 (m, 1H), 4.05 (m, 1H), 3.87 (m, 1H), 3.70 (m, 3H), 3.36 (m, 2H), 3.12 (m, 1H), 2.75-2.58 (m, 1H), 2.01 (m, 2H), 1.76 (m, 2H), 1.45 (m, 2H); MS (ESI(+)) m/e 420 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09302989B2
Source datasetuspto-grants-2016_04
ORD IDord-e31568e5a8614a92886578aa37ebbc28
Source noteuspto-grants-2016_04