HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624259Generated: October 30, 2026
Homoallyl bromide → HCID 68750609, compound
https://huagongshe.com/reaction/624259
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Homoallyl bromide | HCID 21241 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 6-Chloro-4-hydroxy-1,2-dihydroquinolin-2-one | HCID 54705762 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 68750609 | HCID 68750609 | — |
Reaction Steps
To a solution of 6-chloro-4-hydroxyquinolin-2(1H)-one (800 mg, 4.09 mmol) and N,N-diisopropylethylamine (1415 μl, 8.18 mmol) in dimethylformamide (13.6 ml) was added 4-bromo-1-butene (415 μl, 4.09 mmol). The solution was heated to 60° C. and stirred for 18 hours. The reaction mixture was purified by column chromatography to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09302989B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-04064d47bde24dc28b983b5cec8bc57b |
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| Source note | uspto-grants-2016_04 |
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