HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triacetoxyperiodinane → Benzyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triacetoxyperiodinane | HCID 159087 | — |
| Reactant | HCID 67126666 | HCID 67126666 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Benzyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate | HCID 59803011 | — |
Reaction Steps
To a solution of EXAMPLE 391C (23.66 g) in dichloromethane (350 mL) was added Dess-Martin Periodinane (33.1 g). The mixture was stirred overnight. The mixture was diluted with ethyl acetate (600 mL) and washed with 2N aqueous NaOH, water, and brine. After drying over Na2SO4, the mixture was filtered and concentrated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09303025B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-66ad7ab3d41c42e5910013e2da2ea0aa |
| Source note | uspto-grants-2016_04 |