2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine--hydrogen chloride (1/1) → HCID 59676089, compound

HRID 624495Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:9]2[NH:8][C:7]3[C:12]4[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=4[O:14][C:6]=3[C:5]=2[CH:4]=1.Cl.Cl[CH2:21][C:22]1[CH:35]=[CH:34][C:25]([O:26][CH2:27][CH2:28][N:29]([CH2:32][CH3:33])[CH2:30][CH3:31])=[CH:24][CH:23]=1>>[CH2:32]([N:29]([CH2:30][CH3:31])[CH2:28][CH2:27][O:26][C:25]1[CH:24]=[CH:23][C:22]([CH2:21][N:8]2[C:9]3[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[CH:4][C:5]=3[C:6]3[O:14][C:13]4[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=4[C:7]2=3)=[CH:35][CH:34]=1)[CH3:33]

Participants

Reactant 2

HCID 124936922-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine--hydrogen chloride (1/1)

HCID 59676106HCID 59676106, compound

Product 1

HCID 59676089HCID 59676089, compound

Procedure

Following the procedure described in Example 102, using 3-methoxy-10H-benzo[4,5]furo[3,2-b]indole (405 mg, 1.517 mmol) and [2-(4-chloromethyl-phenoxy)-ethyl]-diethyl-amine hydrochloride salt as a starting material, the title compound was prepared as a brown solid.

Sources & evidence

ORD record: ord-82ba4958ff5d4744a6d12cf4b36c0f42
Source dataset: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09303037B2

Reaction notes

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