5-Chloro-2-furaldehyde → HCID 76284846, compound

HRID 624572Notes

Reaction equation

HRID 624572 reaction equation
[OH:1][C:2]([CH3:24])([CH3:23])[CH2:3][N:4]1[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:11]2[C:6]([N:7]([CH3:22])[C:8](=[O:21])[N:9]([CH3:20])[C:10]2=[O:19])=[CH:5]1.[Cl:25][C:26]1[O:30][C:29]([CH:31]=O)=[CH:28][CH:27]=1>C1(C)C=CC=CC=1>[Cl:25][C:26]1[O:30][C:29]([CH:31]2[C:5]3=[C:6]4[N:7]([CH3:22])[C:8](=[O:21])[N:9]([CH3:20])[C:10](=[O:19])[C:11]4=[C:12]([C:13]4[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=4)[N:4]3[CH2:3][C:2]([CH3:24])([CH3:23])[O:1]2)=[CH:28][CH:27]=1

Participants

4

Reactant 2

HCID 27696305-Chloro-2-furaldehydeHCID 90219056HCID 90219056, compound

Product 1

HCID 76284846HCID 76284846, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The title compound was prepared from 6-(2-hydroxy-2-methylpropyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione and commercially available 5-chlorofuran-2-carbaldehyde in toluene analogously to Example 12, step 2;

Sources & evidence

ORD record
ord-2aa29ec68eb54e4c833c549bb99b1f4d
Source dataset
uspto-grants-2016_04
Patent number
US09303035B2

Reaction notes

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