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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624590Generated: November 3, 2026

4-Fluorobenzoyl chloride → 6-(2-Amino-ethyl)-5-(4-fluoro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione

https://huagongshe.com/reaction/624590

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoyl chlorideHCID 67879—
Reactant6-(2-Amino-ethyl)-1,3-dimethyl-5-phenyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dioneHCID 86722879—
Product6-(2-Amino-ethyl)-5-(4-fluoro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dioneHCID 86722911—

Reaction Steps

This compound was prepared analogously to Intermediate A by replacing benzoyl chloride (step 2) with 4-fluorobenzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09303035B2
Source datasetuspto-grants-2016_04
ORD IDord-7197b6a1a33844d499dd3b81e6754682
Source noteuspto-grants-2016_04