3-Bromoanisole → HCID 86722919, compound

HRID 624598Notes

Reaction equation

HRID 624598 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15](Cl)[CH:14]=2)=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1.BrC1C=[C:27]([O:31]C)C=CC=1>>[NH2:1][CH2:2][CH2:3][N:4]1[C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:31][CH3:27])[CH:14]=2)=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1

Participants

3

Reactant 2

HCID 169713-BromoanisoleHCID 867228806-(2-Amino-ethyl)-5-(3-chloro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione

Product 1

HCID 86722919HCID 86722919, compound

Procedure

The title compound was prepared analogously to Intermediate B by replacing 1-bromo-3-chlorobenzene with 3-bromoanisole;

Sources & evidence

ORD record
ord-4d419bdd7d584767b6779a21249b87fd
Source dataset
uspto-grants-2016_04
Patent number
US09303035B2

Reaction notes

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