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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624599Generated: October 26, 2026

Benzene, 1-bromo-3,5-dimethyl- → 6-(2-Aminoethyl)-5-(3,5-dimethylphenyl)-1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

https://huagongshe.com/reaction/624599

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-bromo-3,5-dimethyl-HCID 136357—
Reactant6-(2-Amino-ethyl)-5-(3-chloro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dioneHCID 86722880—
Product6-(2-Aminoethyl)-5-(3,5-dimethylphenyl)-1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dioneHCID 86722920—

Reaction Steps

The title compound was prepared analogously to Intermediate B by replacing 1-bromo-3-chlorobenzene with 1-bromo-3,5-dimethylbenzene;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09303035B2
Source datasetuspto-grants-2016_04
ORD IDord-5a227009cea84688a69d34ade3af5fa5
Source noteuspto-grants-2016_04