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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624601Generated: October 26, 2026

3-Bromobenzonitrile → 3-(6-(2-Aminoethyl)-1,3-dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrile

https://huagongshe.com/reaction/624601

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromobenzonitrileHCID 23381—
Reactant6-(2-Amino-ethyl)-5-(3-chloro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dioneHCID 86722880—
Product3-(6-(2-Aminoethyl)-1,3-dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrileHCID 86722922—

Reaction Steps

The title compound was prepared analogously to Intermediate B by replacing 1-bromo-3-chlorobenzene with 3-bromobenzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09303035B2
Source datasetuspto-grants-2016_04
ORD IDord-9135a2780cac4795b3ca019c7cabafd4
Source noteuspto-grants-2016_04