2-Iodo-4-methyl-1,3-thiazole → HCID 86722923, compound

HRID 624602Notes

Reaction equation

HRID 624602 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[C:12]([C:13]2C=CC=C(Cl)C=2)=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1.IC1[S:26][CH:27]=[C:28]([CH3:30])[N:29]=1>>[NH2:1][CH2:2][CH2:3][N:4]1[C:12]([C:13]2[S:26][CH:27]=[C:28]([CH3:30])[N:29]=2)=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1

Participants

3

Reactant 2

HCID 231545942-Iodo-4-methyl-1,3-thiazole2×HCID 867228806-(2-Amino-ethyl)-5-(3-chloro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione

Product 1

HCID 86722923HCID 86722923, compound

Procedure

The title compound was prepared analogously to Intermediate B by replacing 1-bromo-3-chlorobenzene with 2-iodo-4-methylthiazole (Intermediate F)

Sources & evidence

ORD record
ord-a24fd4b8db5a48edb9b1805f9c71194a
Source dataset
uspto-grants-2016_04
Patent number
US09303035B2

Reaction notes

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