N'-(propan-2-ylidene)(tert-butoxy)carbohydrazide → N'-(propan-2-yl)(tert-butoxy)carbohydrazide

HRID 624626Notes

Reaction equation

HRID 624626 reaction equation
[CH3:1][C:2](=[N:4][NH:5][C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7])[CH3:3].[H][H]>[Pd].C(O)(=O)C.CO>[CH:2]([NH:4][NH:5][C:6]([O:8][C:9]([CH3:11])([CH3:10])[CH3:12])=[O:7])([CH3:3])[CH3:1]

Participants

6

Reactant 2

HCID 11435207N'-(propan-2-ylidene)(tert-butoxy)carbohydrazideHCID 178418361HCID 178418361, compound

Product 1

HCID 11217534N'-(propan-2-yl)(tert-butoxy)carbohydrazide

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolventHCID 887MethanolSolvent

Procedure

tert-Butyl 2-(propan-2-ylidene)hydrazinecarboxylate 2 was reduced with palladium catalyst on carbon with hydrogen gas in acetic acid and methanol to give tert-butyl 2-isopropylhydrazinecarboxylate 3 (CAS Reg. No. 16689-35-3).

Sources & evidence

ORD record
ord-bde8e15a9ed14be587b08c5b6b393b39
Source dataset
uspto-grants-2016_04
Patent number
US09303043B2

Reaction notes

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