HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium trimethylsilanolate → HCID 90031924, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium trimethylsilanolate | HCID 23668039 | — |
| Reactant | HCID 90031463 | HCID 90031463 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 90031924 | HCID 90031924 | — |
Reaction Steps
A solution of methyl 1-(1-methyl-1H-imidazol-5-yl)-1H-indole-3-carboxylate (40 mg, 0.157 mmol) in THF (1567 μl) was treated with potassium trimethylsilanolate (223 mg, 1.567 mmol) in one portion at RT and the resulting reaction mixture stirred overnight. ISCO purification (10% MeOH/DCM) afforded the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09303045B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-37cc8b661dc64c53bfc7b6df532ec071 |
| Source note | uspto-grants-2016_04 |