Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 624858Generated: October 27, 2026

Diisopropylethylamine → HCID 90203433, compound

https://huagongshe.com/reaction/624858

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant(3-Methyloxetan-3-yl)methanamineHCID 15789550—
Reactant6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acidHCID 71087292—
ProductHCID 90203433HCID 90203433—

Reaction Steps

In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with (3-methyloxetan-3-yl)methanamine (CAN 153209-97-3) in the presence of TBTU and DIEA to give the title compound as a byproduct as colorless oil; MS (EI): m/e=368.5 [MH+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09303012B2
Source datasetuspto-grants-2016_04
ORD IDord-5bb9fb08774e468f8bb0167b45be936d
Source noteuspto-grants-2016_04