HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(benzyl(methyl)amino)-N-(2-methoxyethyl)propanamide → N-(2-methoxyethyl)-3-(methylamino)propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(benzyl(methyl)amino)-N-(2-methoxyethyl)propanamide | HCID 66586806 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-(2-methoxyethyl)-3-(methylamino)propanamide | HCID 43827811 | 28.4% |
Reaction Steps
To a solution of 3-(benzyl(methyl)amino)-N-(2-methoxyethyl)propanamide (1.1 g, 4.39 mmol, 1.00 equiv) in methanol (50 mL) was added 5% palladium-on-carbon (50 mg) and the suspension stirred under a hydrogen atmosphere for 2 h. The solids were filtered out and the mixture was concentrated under vacuum to afford 200 mg (28%) of the product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09301951B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-c0bc024276584e508e5968bdece29247 |
| Source note | uspto-grants-2016_04 |