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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 625440Generated: October 30, 2026

Cyclopentanol → (S)-2-(2-amino-5-(cyclopentyloxy)phenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)isonicotinamide

https://huagongshe.com/reaction/625440

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanolHCID 7298—
Reactant(S)-2-(2-amino-5-cyclobutoxyphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)isonicotinamideHCID 66586878—
Product(S)-2-(2-amino-5-(cyclopentyloxy)phenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)isonicotinamideHCID 67517563—

Reaction Steps

This intermediate was prepared according to the procedure described for the synthesis of (S)-2-(2-amino-5-cyclobutoxyphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)isonicotinamide Example 132, using cyclopentanol in place of cyclobutanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09301951B2
Source datasetuspto-grants-2016_04
ORD IDord-75b7af76e06a460ab56adaab80369427
Source noteuspto-grants-2016_04