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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 62565Generated: October 29, 2026

Piperidine → HCID 57323224, compound

https://huagongshe.com/reaction/62565

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
ReactantPyrrolidineHCID 31268—
Reactant3,5-Di-tert-butyl-4-hydroxybenzaldehydeHCID 73219—
ProductHCID 57323224HCID 57323224—

Reaction Steps

In lieu of piperidine, pyrrolidine was used with 3,5-di-tert-butyl-4-hydroxybenzaldehyde to synthesize the subsequent intermediate 7-pyrrolidinyl quinone methide following the procedure in Example 1 (d). The remainder of the one-pot procedure towards 7-Phace-QM is as detailed in Example 1 (d).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447002B2
Source datasetuspto-grants-2016_09
ORD IDord-320674cebadf4dd48475c71140601242
Source noteuspto-grants-2016_09