HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 14651533, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | (R)-1-Methyl hydrogen 3-methylglutarate | HCID 6999733 | — |
| Product | HCID 14651533 | HCID 14651533 | — |
Reaction Steps
Scheme 1 illustrates an exemplary method for making a compound of the formula 1.3. Starting from (R)-5-methoxy-3-methyl-5-oxopentanoic acid, reaction with methyl chloroformate gives (R)-5-methoxy-4-(methoxycarbonyl)-3-methyl-5-oxopentanoic acid, which can be esterified with, for example, trimethylsilyl chloride and methanol to give compound 1.3, (R)-trimethyl 2-methylpropane-1,1,3-tricarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309204B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-58fb4dbe6f734f54bf72d38c347f879f |
| Source note | uspto-grants-2016_04 |