HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl malonate → HCID 13964180, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl malonate | HCID 7943 | — |
| Reactant | Methyl Crotonate | HCID 638132 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Product | HCID 13964180 | HCID 13964180 | — |
Reaction Steps
Scheme 2 illustrates an alternative exemplary method for making a compound of the formula 1.3. Starting from (E)-methyl but-2-enoate, reaction with dimethyl malonate and sodium methoxide gives trimethyl 2-methylpropane-1,1,3-tricarboxylate, which can be resolved, by for example, a lipase, to give compound 1.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309204B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-2e87f7db63134dff894446b19cb72a54 |
| Source note | uspto-grants-2016_04 |