HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethylguaiacol → 2-(Benzyloxy)-4-ethyl-1-(2-fluoro-4-nitrophenoxy)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethylguaiacol | HCID 62465 | — |
| Reactant | 1,2-Difluoro-4-nitrobenzene | HCID 123053 | — |
| Reactant | 2-(Benzyloxy)-4-ethylphenol | HCID 59191243 | — |
| Product | 2-(Benzyloxy)-4-ethyl-1-(2-fluoro-4-nitrophenoxy)benzene | HCID 59191238 | 107.6% |
Reaction Steps
According to the procedure of example 20 (a) except substituting 1-fluoro-4-nitro-2-(trifluoromethyl)benzene for 3,4-difluoronitrobenzene (30.5 g; 192 mmol), and 2-methoxy-4-ethylphenol for 2-(benzyloxy)-4-ethylphenol (33.6 g; 147 mmol) the title compound (58.1 g; 100%) was prepared as a brown oil, used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309179B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-9e143fb345f54f95b5f8c456ae508533 |
| Source note | uspto-grants-2016_04 |