3-Butyn-1-OL → HCID 59191301, compound

Participants

Reaction Steps

According to the procedure of example 11 (a) except substituting 5-bromo-2-(2-methoxy-4-propylphenoxy)pyridine by 4-bromo-1-(2-fluoro-4-nitrophenoxy)-2-methoxybenzene (0.29 mmol; 100 mg) and 3-butyn-1-ol by 2-ethynylpyridine (0.73 mmol; 73 μL), the title compound was prepared as a yellow solid (81%; mg) after purification on preparative TLC (cyclohexane/ethyl acetate: 7/3).

Provenance & Evidence