HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Fluoro-4-methoxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Fluoro-4-methoxybenzoic acid | HCID 2733401 | — |
| Product | 3-Fluoro-4-methoxybenzoyl chloride | HCID 2779255 | — |
Reaction Steps
3-Fluoro-4-methoxybenzoic acid (830 mg, 4.88 mmol) and thionyl chloride (10 mL) were refluxed for 2 h. The excess thionyl chloride was removed by repeated evaporation with dry toluene in vacuo, giving the subtitle compound as a brown solid, which would be used for the next step directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309211B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-bf4832730a784fb98c219e4e9ec3944f |
| Source note | uspto-grants-2016_04 |