反应详情

Following general procedure of McMurry reaction as described in example 1, step B, (4-(3-(pyrrolidin-1-yl)propyl)phenyl)(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)methanone (798 mg, 2 mmol) was reacted with propiophenone (800 mg, 6 mmol) to give 208 mg desired product (25%, Z/E=1/1). m/z=412[M+1]+.

1. customgeneral procedure of McMurry reaction