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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 62622Generated: October 25, 2026

alpha-Methyl-4-(2-methylpropyl)benzeneacetyl chloride → 3-Acetamidobicyclo[1.1.1]pentan-1-yl 2-(4-isobutylphenyl)propanoate

https://huagongshe.com/reaction/62622

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Methyl-4-(2-methylpropyl)benzeneacetyl chlorideHCID 595157—
ReactantN-{3-hydroxybicyclo[1.1.1]pentan-1-yl}acetamideHCID 86287953—
Product3-Acetamidobicyclo[1.1.1]pentan-1-yl 2-(4-isobutylphenyl)propanoateHCID 86288028—

Reaction Steps

The general procedure of Example 1 Step 3 is repeated starting with N-(3-hydroxybicyclo[1.1.1]pentan-1-yl)acetamide (1) and using 2-(4-isobutylphenyl)propanoyl chloride in place of the acetyl chloride to produce compound 9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447026B2
Source datasetuspto-grants-2016_09
ORD IDord-8bbe225f27ca4062ab6ca60f23cbc351
Source noteuspto-grants-2016_09