HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Amino-3-nitrophenyl)propan-1-one → 1-(3,4-Diaminophenyl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Amino-3-nitrophenyl)propan-1-one | HCID 89672887 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(3,4-Diaminophenyl)propan-1-one | HCID 20216558 | 90.1% |
Reaction Steps
To a solution of 1-(4-amino-3-nitrophenyl)propan-1-one (1.94 g, 10 mmol) in 50 mL of methanol was added 0.5 g 10% Pd/C and the mixture was hydrogenated under H2 (1 atm) at rt for 1 h. The mixture was filtered and the filtrated was concentrated to give the desired product (1.48 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309211B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-49f40f8b37384c6aacd54554f6d4a0a7 |
| Source note | uspto-grants-2016_04 |