Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 626235Generated: October 30, 2026

1-(4-Amino-3-nitrophenyl)propan-1-one → 1-(3,4-Diaminophenyl)propan-1-one

https://huagongshe.com/reaction/626235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Amino-3-nitrophenyl)propan-1-oneHCID 89672887—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product1-(3,4-Diaminophenyl)propan-1-oneHCID 2021655890.1%

Reaction Steps

To a solution of 1-(4-amino-3-nitrophenyl)propan-1-one (1.94 g, 10 mmol) in 50 mL of methanol was added 0.5 g 10% Pd/C and the mixture was hydrogenated under H2 (1 atm) at rt for 1 h. The mixture was filtered and the filtrated was concentrated to give the desired product (1.48 g, 90%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09309211B2
Source datasetuspto-grants-2016_04
ORD IDord-49f40f8b37384c6aacd54554f6d4a0a7
Source noteuspto-grants-2016_04