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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 626324Generated: October 30, 2026

HCID 89964223, compound → Iberdomide

https://huagongshe.com/reaction/626324

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 89964223HCID 89964223—
CatalystPalladiumHCID 23938—
SolventAcetic AcidHCID 176—
ProductIberdomideHCID 67335295—

Reaction Steps

(S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione is prepared from (S)-1-benzyl-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione by hydrogenation in acetic acid in the presence of Pd/C for 2 days.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09309220B2
Source datasetuspto-grants-2016_04
ORD IDord-2c74ade9432644d997d76c5f3284ff46
Source noteuspto-grants-2016_04