Sodium Acetate → HCID 90057964, compound

HRID 626342Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][C:3]=1[NH:15][C:16]([C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[C:20]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([F:34])[CH:29]=2)[CH:19]=1)=[O:17].CC([O-])=O.[Na+]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][C:3]=1[NH:15][C:16]([C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[C:20]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([F:34])[CH:29]=2)[CH:19]=1)=[O:17]

Participants

Reactant 2

HCID 517045Sodium Acetate

HCID 90057965HCID 90057965, compound

Product 1

HCID 90057964HCID 90057964, compoundYield 80%

Procedure

Compound 19 was synthesized from 16b (4.37 mmol), p-tolylsulfonyl hydrazide (13.1 mmol) and NaOAc (39.3 mmol) using the procedure according to Method F described above.

Sources & evidence

ORD record: ord-7cb4a41d6c434319bc0a559a316da263
Source dataset: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09309187B2

Reaction notes

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