HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-[2-(2,5-Dioxo-pyrrolidin-1-yl)-ethoxy]-3-methoxy-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Succinimide | HCID 11439 | — |
| Reactant | 4-(2-Bromoethoxy)-3-methoxybenzaldehyde | HCID 16087294 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-[2-(2,5-Dioxo-pyrrolidin-1-yl)-ethoxy]-3-methoxy-benzaldehyde | HCID 89610696 | — |
Reaction Steps
B method: 11.66 g (45 mmol) of 4-(2-bromo-ethoxy)-3-methoxy-benzaldehyde (6.2) and 4.46 g (45 mmol) pyrrolidine-2,5-dione (7.2) is heated with 8.28 g (60 mmol) K2CO3 in 200 ml of acetonitrile for 8 h. After same isolation procedure as in A method 4.1 is given with same purity.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447038B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-cae274ee38054a5080d6f1068ecce66f |
| Source note | uspto-grants-2016_09 |