HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 626463Generated: October 30, 2026
2-(4-Chlorophenyl)ethylamine → HCID 72192372, compound
https://huagongshe.com/reaction/626463
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-(4-Chlorophenyl)ethylamine | HCID 67430 | — |
| Reactant | Ethyl 4-hydroxy-2-(methylsulfanyl)-5-pyrimidinecarboxylate | HCID 239049 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 72192372 | HCID 72192372 | 25.2% |
Reaction Steps
The mixture of ethyl 2-(methylthio)-6-oxo-1,6-dihyropyrimidine-5-carboxylate (333 mg, 1.554 mmol) and 2-(4-chlorophenyl)ethanamine (242 mg, 1.554 mmol) were dissolved in 10 mL of ethanol and heated at 80° C. overnight. After heating, the solution was run on thin layer chromatography and filtered. The precipitate was collected and stored. 1H-NMR confirmed the product (126 mg, 25.2% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09309232B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-d804802ae42749e7b47a4094db9713f9 |
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| Source note | uspto-grants-2016_04 |
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