HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → [9-(Prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (tert-butoxy)-N'-[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]carbohydrazide | HCID 68314800 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | [9-(Prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]hydrazine | HCID 68314598 | 112.1% |
Reaction Steps
A solution of (tert-butoxy)-N′-[9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]carbohydrazide (0.33 g, 1.06 mmol) in 4 mL of EtOAc was added 4M HCl in dioxane at rt. The solution was stirred at rt until reaction completion, monitored by LC-MS (30 h). The solvent was then removed to give [9-(prop-2-en-1-yl)-6-oxaspiro[4.5]decan-9-yl]hydrazine (250 mg). LCMS m/z 211.1 (M+1) observed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309234B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-f8e8c21a55af4102b3300b4f714a25d9 |
| Source note | uspto-grants-2016_04 |