HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperonal → 6-Benzyloxy-4-methyl-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperonal | HCID 8438 | — |
| Reactant | 5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid | HCID 907391 | — |
| Reactant | 2-Methyl 4-benzyloxybenzaldehyde | HCID 2759806 | — |
| Product | 6-Benzyloxy-4-methyl-1H-indole-2-carboxylic acid | HCID 69280231 | — |
Reaction Steps
Intermediate I-5a was prepared using procedures analogous to those described above for the synthesis of 5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid (I-4c) using 4-(benzyloxy)-2-methylbenzaldehyde (I-4c) as the starting material instead of benzo[d][1,3]dioxole-5-carbaldehyde. ESI MS: m/z 282.24 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447039B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-1afba8ef7f84416c8027ab29ea0dea06 |
| Source note | uspto-grants-2016_09 |