HCID 178504782, compound → 2-(2,6-dichloro-4-methanesulfonylphenyl)-2H-pyrazolo[4,3-c]pyridine

Participants

Reaction Conditions

Reaction Steps

A mixture of [1-(4-azidopyridin-3-yl)meth-(E)-ylidene]-(2.6-dichloro-4-methanesulfonylphenyl)amine (4.21 mmol) in toluene (15 mL) was heated to 105° C. for 18 hours. The reaction mixture was allowed to cool and then concentrated under reduced pressure. The residue was recrystallised from ethyl acetate and the solid was collected by filtration to afford the title compound as a beige solid (0.75 g, 52% yield). 1H NMR (300 MHz, DMSO-d6): δ 9.38 (d, J=1.4 Hz, 1H) 9.15 (d, J=1.0 Hz, 1H), 8.34 (s, 2H) 8.31 (d, J=6.4 Hz, 1H) 7.68 (dt, J=6.4, 1.2 Hz, 1H) 3.49 (s, 3H). LCMS (Method D): RT=1.72 min, m/z: 342 [M+H+].

Provenance & Evidence