HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dichloro-4-(7-chloropyrazolo[4,3-c]pyridin-2-yl)benzonitrile → 7-Chloro-2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dichloro-4-(7-chloropyrazolo[4,3-c]pyridin-2-yl)benzonitrile | HCID 69671622 | — |
| Reactant | HCID 178514505 | HCID 178514505 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 7-Chloro-2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine | HCID 69671438 | 66% |
Reaction Steps
Following the procedure described for 3,5-dichloro-4-(7-chloropyrazolo[4,3-c]pyridin-2-yl)benzonitrile, [1-(4-azido-5-chloropyridin-3-yl)-meth-(E)-ylidene]-(2,6-dichlorophenyl)-amine was heated under reflux in toluene to afford the title compound as a brown solid (2.7 g, 66% yield). LCMS (Method D): RT=2.96 min, m/z: 298 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309240B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-ff73126777e0486ea8f5fac30fcc1e69 |
| Source note | uspto-grants-2016_04 |