HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-4-chloropyridine → 5-Bromo-4-chloropyridine-3-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-4-chloropyridine | HCID 817696 | — |
| Reactant | 4,5-Dichloropyridine-3-carbaldehyde | HCID 59596580 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Bromo-4-chloropyridine-3-carbaldehyde | HCID 71742307 | 73% |
Reaction Steps
Following the procedure described for 4,5-dichloropyridine-3-carbaldehyde, 3-bromo-4-chloropyridine and DMF were reacted to afford the title compound as a white solid (3.74 g, 73% yield). 1H NMR (300 MHz, CDCl3): δ 10.48 (d, J=0.4 Hz, 1H), 8.95-8.92 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309240B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-6dc8ca6f55e846a2a23bc86ea847bcb5 |
| Source note | uspto-grants-2016_04 |