4-Amino-3,5-dichlorobenzonitrile → HCID 178509962, compound

HRID 626726Notes

Reaction equation

HRID 626726 reaction equation
[N:1]([C:4]1[C:9](Cl)=[CH:8][N:7]=[CH:6][C:5]=1/[CH:11]=[N:12]/[C:13]1[C:20]([Cl:21])=[CH:19][C:16]([C:17]#[N:18])=[CH:15][C:14]=1[Cl:22])=[N+:2]=[N-:3].N(C1C([Br:32])=CN=CC=1C=O)=[N+]=[N-].NC1C(Cl)=CC(C#N)=CC=1Cl>>[N:1]([C:4]1[C:9]([Br:32])=[CH:8][N:7]=[CH:6][C:5]=1/[CH:11]=[N:12]/[C:13]1[C:20]([Cl:21])=[CH:19][C:16]([C:17]#[N:18])=[CH:15][C:14]=1[Cl:22])=[N+:2]=[N-:3]

Participants

4

Reactant 3

HCID 5227064-Amino-3,5-dichlorobenzonitrileHCID 866970574-Azido-5-bromo-pyridine-3-carbaldehydeHCID 178509964HCID 178509964, compound

Product 1

HCID 178509962HCID 178509962, compound

Procedure

Following the procedure described for 4-{[1-(4-azido-5-chloropyridin-3-yl)meth-(E)-ylidene]amino}-3,5-dichlorobenzonitrile, 4-azido-5-bromo-pyridine-3-carbaldehyde and 4-amino-3,5-dichlorobenzonitrile were reacted to afford the title compound as a beige solid (quant. yield) that was used without purification.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-df7438626fc84fb9bd3d7d3d5ec34990
Source dataset
uspto-grants-2016_04
Patent number
US09309240B2

Reaction notes

Loading…