HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dichloro-4-(7-chloropyrazolo[4,3-c]pyridin-2-yl)benzonitrile → 7-bromo-2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dichloro-4-(7-chloropyrazolo[4,3-c]pyridin-2-yl)benzonitrile | HCID 69671622 | — |
| Reactant | HCID 178514475 | HCID 178514475 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 7-bromo-2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine | HCID 69671391 | 81% |
Reaction Steps
Following the procedure described for 3,5-dichloro-4-(7-chloropyrazolo[4,3-c]pyridin-2-yl)benzonitrile, [1-(4-azido-5-bromopyridin-3-yl)-meth-(E)-ylidene]-(2,6-dichlorophenyl)-amine was heated under reflux in toluene to afford the title compound as a brown solid (7.5 g, 81% yield). LCMS (Method D): RT=2.90 min, m/z: 344 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309240B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-f817dc899dfc424cb8b2f29523dc83c5 |
| Source note | uspto-grants-2016_04 |