(2-Chloropyrimidin-5-yl)boronic acid → HCID 131735234, compound

HRID 626951Notes

Reaction equation

HRID 626951 reaction equation
[O:1]1[CH:7]([C:8]([OH:10])=[O:9])[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.Cl[C:12]1[N:17]=[CH:16][C:15]([B:18]([OH:20])[OH:19])=[CH:14][N:13]=1>>[B:18]([C:15]1[CH:14]=[N:13][C:12]([N:4]2[CH2:5][CH2:6][CH:7]([C:8]([OH:10])=[O:9])[O:1][CH2:2][CH2:3]2)=[N:17][CH:16]=1)([OH:20])[OH:19]

Participants

3

Reactant 2

HCID 21747362(2-Chloropyrimidin-5-yl)boronic acidHCID 83672274HCID 83672274, compound

Product 1

HCID 131735234HCID 131735234, compound

Procedure

The title compound was prepared from 1,4-oxazepane-7-carboxylic acid and (2-chloropyrimidin-5-yl)boronic acid in accordance with General Method C.

Sources & evidence

ORD record
ord-2dae046bbb604301b5f6ba7b289df54a
Source dataset
uspto-grants-2016_04
Patent number
US09309243B2

Reaction notes

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