HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Chloropyrimidin-5-yl)boronic acid → HCID 131735240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Chloropyrimidin-5-yl)boronic acid | HCID 21747362 | — |
| Reactant | Methyl 3-azabicyclo[3.2.1]octane-8-carboxylate hydrochloride | HCID 72207893 | — |
| Product | HCID 131735240 | HCID 131735240 | 122.7% |
Reaction Steps
Prepared from methyl 3-azabicyclo[3.2.1]octane-8-carboxylate hydrochloride (0.57 g, 2.8 mmol) and (2-chloropyrimidin-5-yl)boronic acid (0.45 g, 2.8 mmol) in accordance with General Method C to afford the title compound (1 g) as an off-white gum. LCMS (pH 3) MH+ 292, RT 0.79 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309243B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-85f7cfed04c944e08b6cfb10f28bd272 |
| Source note | uspto-grants-2016_04 |