HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | methyl 2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methylpentanamido]acetate | HCID 6560406 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride | HCID 18603049 | — |
Reaction Steps
To a solution of (S)-methyl 2-(2-((tert-butoxycarbonyl)amino)-4-methylpentanamido) acetate (3w) in 1,4-dioxane was added a 5M solution of HCl in 1,4-dioxane at room temperature. The reaction was stirred at room temperature for 16 h. The reaction mixture was filtered to afford (S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride (4w) as the filtered solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447030B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-3fac7b9d471e44748fbe1c0c04b75aca |
| Source note | uspto-grants-2016_09 |