HRID627107

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=CCON([C@H]1CN(C(=O)OC(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)C=C1C(=C)C)S(=O)(=O)c1ccccc1[N+](=O)[O-]

HCID89852307

未命名化合物

2 次

结构：C=CCON([C@H]1CN[C@H](C(N)=O)C=C1C)S(=O)(=O)c1ccccc1[N+](=O)[O-]

HCID117940244

未命名化合物

PRODUCTS

生成物

结构：C=CCON([C@H]1CN[C@H](CO[Si](C)(C)C(C)(C)C)C=C1C(=C)C)S(=O)(=O)c1ccccc1[N+](=O)[O-]

HCID89852508

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from (2S,5R)-tert-butyl 5-(N-(allyloxy)-2-nitrophenylsulfonamido)-2-((tert-butyldimethylsilyloxy)methyl)-4-(prop-1-en-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate (Intermediate 54, 3.04 g, 4.87 mmol) following the procedure described for Intermediate 21. The desired product was obtained as an orange oil (2.53 g, 99%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-65d3cc174737428c81e36b7fa121a131
来源数据集: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09309245B2
来源说明: uspto-grants-2016_04

反应 SMILES

[CH2:1]([O:4][N:5]([C@H:18]1[CH2:23][N:22](C(OC(C)(C)C)=O)[C@H:21]([CH2:31][O:32][Si:33]([C:36]([CH3:39])([CH3:38])[CH3:37])([CH3:35])[CH3:34])[CH:20]=[C:19]1[C:40]([CH3:42])=[CH2:41])[S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N+:15]([O-:17])=[O:16])(=[O:8])=[O:7])[CH:2]=[CH2:3].C(ON([C@H]1CN[C@H](C(N)=O)C=C1C)S(C1C=CC=CC=1[N+]([O-])=O)(=O)=O)C=C>>[CH2:1]([O:4][N:5]([C@@H:18]1[C:19]([C:40]([CH3:42])=[CH2:41])=[CH:20][C@@H:21]([CH2:31][O:32][Si:33]([C:36]([CH3:39])([CH3:38])[CH3:37])([CH3:35])[CH3:34])[NH:22][CH2:23]1)[S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N+:15]([O-:17])=[O:16])(=[O:8])=[O:7])[CH:2]=[CH2:3]